Special Topics in Physio Psych  -  NeuroDevelopment

3 credits
Class size:  19 (mix of graduate students & senior undergrads)
Instructor:  Dr. Holly Fitch
Email: roslyn.h.fitch@uconn.edu
Day:  Tuesday
Time:  3:00PM- 6:00PM
Location:  Bousfield room # 109

Click on papers below to download and print as PDF files.

CLICK HERE FOR UPDATED SYLLABUS (3/29/2011)


Jan 18 -- Snow Day!

Jan 25 – Introduction, distribute syllabus and confirm sign-ups.
Review class format and presentation expectations.
Review of neural and behavioral development and terminology, including milestones and basic assessments (approx 1 hour), Dr. Fitch.
Distribute papers for Feb 1 to presenters.

1) Introductory PowerPoint in PDF.

Feb 1 – NeuroDevelopmental Mechanisms and Genetics   

1) Diaz & Gleeson, 2009, The molecular and genetic mechanisms of neocortex development.

DIAZ&GLEESON Presentation (O'Keefe) in PDF

2) Mitsuhashi & Takahashi, 2009, Genetic regulation of proliferation/differentiation characteristics of neural progenitor cells in the developing neocortex.

3) Walsh, 2000, Genetics of neuronal migration in the cerebral cortex.  

TAKAHASHI and WALSH Presentations (Podurgiel, Long) in PDF
        
4) Webb, Monk & Nelson, 2001, Mechanisms of postnatal neurobiological development: Implications for human development.

WEBB & MONK Presentation Part 1 (Smith)
WEBB & MONK Presentation Part 2 (Santerre)

Feb 1 -- Snow day again....

Feb 15 –  NeuroDevelopment, Phylogeny, and Evolution ("Evo-Devo")

1) Willmore, 2010, Development influences evolution.

2) Basar, 2009, Darwin’s evolution theory, brain oscillations, and complex brain function in a new “Cartesian view."

WILLMORE & BASAR Presentations (Long) in PDF

3) Finlay, 1998, Patterns of vertebrate neurogenesis and the paths of vertebrate evolution.

FINLAY Presentation (Podurgiel) in PDF

4) Rakic, 2009, Evolution of the neocortex: a perspective from developmental biology.

RAKIC Presentation (Santerre) in PDF

Feb 22 - No Class

Mar 1 - Perinatal NeuroDevelopment and Vulnerability

1) Rice & Barone, 2000, Critical periods of vulnerability for the developing nervous system: Evidence from humans and animal models.

RICE&BARRONE Presentation (Moritz/Lurie) in PDF

2) Aylward, 2005, Neurodevelopmental outcomes of infants born prematurely.

AYLWARD Presentation (Smith) in PDF

3) El-Dib et al., 2010, Neuroimaging and neurodevelopmental outcome of infants born prematurely.

EL-DIB Presentation (Srinivasan) in PDF

March 8 -- No Class, UConn Spring Break

Mar 15 – Plasticity, Part I. Synaptic circuits and experience.

1) Johnston et al., 2001, Sculpting the developing brain.

JOHNSTON et.al Presentation (O'Keefe,Kanaskar, Skudlarek)

2) Katz & Shatz, 1996, Synaptic activity and the construction of cortical circuits.

KATZ & SHATZ Presentation (Depowski)

3) Randy Nudo, 2006, Plasticity.

NUDO Presentation (Srinvasan)

March 22  – Plasticity, Part II. Deprivation and re-organization.

1) Mauerer et al. 2005, Missing sights: consequences for visual development.

MAURER etal. Presentation (Flynn)

2) Bavelier et al. 2006, Do deaf individuals see better?

BAVELIER et al Presentation (Carrigan) in PDF

3) Finney et al., 2001, Visual stimuli activate auditory cortex in the deaf.

FINNEY etal. Presentation (Spina)

4) Harrison et al., 2005, Is there a critical period for cochlear implantation in congenitally deaf children? Analyses of hearing and speech perception performance after implantation.

(**need Harrison presentation, Deposwski****)

March 29 -- Cognitive NeuroDevelopment.

1) Casey et al., 2005, Imaging the Developing Brain: What Have we Learned about Cognitive Development?
(Note that B.J. Casey is to speak in the Psych Dept. this semester, date/time TBD)

CASEY etal Presentation (Moritz) in PDF

2) Toga et al., 2006, Mapping brain maturation.

TOGA et al Presentation (Depowski) in PDF

3) Kuhl & Rivera-Gaxiola, 2008, Neural Substrates of Language Acquisition.

KUHL & RIVERA-GLAXIOLA Presentation (Carrigan and Park) in PDF

For color version of Kuhl & Rivera-Gaxiola, see:
http://www.annualreviews.org/doi/full/10.1146/annurev.neuro.30.051606.094321

April 5  – Motor Development and Cerebral Palsy

1) Martin, 2005, The corticospinal system: from development to motor control.

MARTIN Presentation (Srinivasan) in PDF

2) Martin et al., 2004, Corticopsinal system development depends on motor experience.

MARTIN et al Presentation (Moritz) in PDF

3) Silbereis et al., 2010, Towards improved animal models of neonatal white matter injury associated with cerebral palsy

SILBEREIS et al. Presentation (Smith-Podurgiel) in PDF

4) Johnston, 2009. Plasticity in the developing brain: implications for rehabilitation.

JOHNSTON Presentation (Flynn) in PDF

April 12 - LLI/Dyslexia and NeuroDevelopment.           

1) Bishop, 2009, Genes, cognition and communication. Insights from neurodevelopmental disorders.

(***** Need Bishop presentation, Park & Kanaskar*******)

2) Shaywitz & Shaywitz, 2008, Paying attention to reading: The neurobiology of reading and dyslexia.

SHAYWITZ Presentation (Szudlarek,Jasminiski, Kurian)

April 19 – Autism and NeuroDevelopment

1) Geschwind and Levitt, 2007, Autism spectrum disorders: developmental disconnection syndromes.

GESCHWIND Presentation (Flynn) in PDF

2) Amaral et al., 2008, Neuroanatomy of autism.

AMARAL Presentation (Srinivasan) in PDF

3) Courchesne et al., 2007, Mapping early brain development in autism.

COURCHESNE Presentation (Lurie & Carrigan)

April 26 – William Syndrome and NeuroDevelopment; Savante syndrome

1) Bellugi et al., 1999, Bridging cognition, the brain and molecular genetics: evidence from Williams syndrome.

(BELLUGI Presentation in PDF (O'Keefe & Spina))

2) Levitin et al., 2004, Characterizing the musical phenotype in individuals with Williams Syndrome.

(LEVITIN Presentation in PDF (Skudlarek, Kurian))

3) Heaton & Wallace, 2004, The savante syndrome.

(HEATON & WALLACE Presentation in PDF (Jasminski))

4) Trefferet, 1999, The savante syndrome and autistic disorder

May 3  – Final class, ADHD and NeuroDevelopment        

1) Durston, 2008, Converging methods in studying attention-deficit/hyperactivity disorder: What can we learn from neuroimaging and genetics?

(DURSTON Presentation (Park & Kurian))

2) Mahone & Wodka, 2008, The neurobiologic profile of girls with ADHD


3) Andersen & Navalta., 2004, Altering the course of neurodevelopment: a framework for understanding the enduring effects of psychotropic drugs.

(ANDERSEN Presentation (Santerre & Spina))